Niacinamide vs Niacin: How is it different and which one to pick? (2024)
Getting the difference between Niacinamide and Niacin can be quite confusing, mainly when checking it out in terms of its chemical names. Niacin and Niacinamide may seem similar, but their differentiation can be a bit tricky and confusing. Although it may seem that both are the same when observed through their names and respective components, but the truth is, they are not!
In this guide will discuss all the factors that differentiate Niacin and Niacinamide from each other and help you clarify your doubt about which niacin supplement to pick!
Table of Contents
Is there any difference between Niacin and Niacinamide?
Yes, Niacin and Niacinamide have vital differences. Niacin is among the essential nutrients of our body that prevents us from various hazardous consequences, while Niacinamide is the form of Niacin. Niacinamide is derived from Niacin, and your body can convert Niacin into Niacinamide. Thus, there are some vital differences between these vitamin B3 components.
The most significant factor that differentiates Niacin from Niacinamide is that Niacin can be converted into Niacinamide by our body but not the other way around.
Another significant difference between Niacin and Niacinamide is that Niacinamide can be produced with the help of an amino acid in your body called Tryptophan in your body, but Niacin cannot. Though these two are used interchangeably, but they have different properties. People who are sensitive to their effects and symptoms may use one over the other as their physical effects differ within the body.
Niacin is well-known as Vitamin B3 or Nicotinic acid helps in maintaining healthy levels of good cholesterol and burning lousy cholesterol.
Similar to other Vitamin B supplements, Niacin helps in retaining the healthy metabolic rate of the body. It is also effective for preventing pellagra, which is a disease caused due to deficiency of Niacin in the body.
Side-effects of Niacin
Niacin supplements will not cause drowsiness but can cause some minor ailments. Some of the usual side effects of Niacin include – Nausea, Vomiting, Diarrhea, Face redness or warming, Cough, and itching.
If those effects are observed in mild forms and if they are increasing and are not recovering, talk to a doctor immediately. Serious side effects take place like –
Muscle issues (tenderness, pain, muscle weakness)
Liver issues (loss of appetite, dark-colored urine, yellowish discoloration of skin or eyes, upper stomach pain, tiredness, or weakness).
What is Niacinamide, and what are its uses and side effects?
There are two form of Vitamin B3 and one of the forms namely Niacinamide is obtained from green vegetables, meat, milk, beans, and eggs. Whenever you intake more Niacin than required by your body, the excess gets transformed into Niacinamide. It is found in many of the vitamin supplements either alone or in the combined form with other vitamins and Niacinamide is also available in topical forms, such as creams, lotions, gels, and serum which is used for reducing inflammations, curing certain types of skin conditions and also helps keep your skin smooth and moisturized. Hence, you must not get confused between Niacinamide with Niacin – which are forms of vitamin B3.
Benefits and use of Niacinamide
Apart from being a preferable form of Niacin to treat pellagra, Niacinamide has various health benefits and uses, like helping in some of the skin conditions, preventing Melanoma, and eliminating chronic kidney disease.
Niacinamide is also beneficial to slow down type 1 diabetes. Some of the other uses of Niacinamide are discussed below –
Acne – Studies and research prove that Niacinamide has anti-inflammation properties, which helps to deal with acne. It is advised to use Niacinamide as a topical treatment or as an oral supplement, for acne-prone skin.
Cancer – Studies are being published, which shows that Niacinamide is valuable and efficient in reducing the risk associated with cancer. It was observed in those participants who are at high risk of skin cancer consumed Niacinamide over one year brought down the risk percentage of cell carcinoma and squamous cell carcinoma by around 23%.
Diabetes – Some of the studies have recommended that Niacinamide is efficient to prevent and treat insulin-dependent diabetes in the early and prediabetic phases of the disorder.
Osteoarthritis – As per various research and studies, consuming niacinamide supplements may be fruitful to treat osteoarthritis with the improvement in flexibility of joints and reduction in inflammation.
And it is also beneficial for the treatment of hyperpigmentation, melasma, and hyperphosphatemia. Niacinamide supplements can also be effective in lowering blood pressure, preventing motion illness, or any other conditions, but there is still no evidence to prove these facts.
Side effects –
Niacinamide is usually considered safe to consume, but minor side effects can be observed while consuming niacinamide supplements like dizziness, heartburn, mild headaches, flatulence, and diarrhea. Some of the side effects of niacinamide creams are burning, mild itching, and redness.
In addition, when it is taken in high doses, like more than 3 grams every day, then Niacinamide can have a toxic or harmful result on the liver. Niacinamide is sanctioned in suitable doses, mainly because massive amounts are released through your urine daily. The permissible upper limit of Vitamin B3 is 35 mg per day.
With Niacinamide aka, nicotinamide, some of the minor side effects are reported like –
Increase insulin resistance (evidence is still inconsistent).
Therefore, we recommend consulting with your healthcare provider or doctor before intaking any supplement with Niacinamide or any other for evaluating individual risk beforehand.
Be careful before taking Niacinamide if you –
Have diabetes
Have gout
Have liver disease
Are breastfeeding or pregnant
Facing gallbladder disease
Also, you should stay away from alcohol consumption when you intake niacinamide supplements.
What is the Best Niacin Vitamin B3 Supplement that one can take without side effects or severe flushing?
NiacinMax is the best Niacin Vitamin B3 supplement, which anybody can take without any flushing issues or side effects as it uses Niacin in recommended doses. It is a supplement originated for unleashing your performance as an athlete by giving an added push to the blood oxygen levels. NiacinMax is mainly consumed by athletes for gaining endurance, strength, and remain energized for the entire performance where even one millisecond matters a lot.
What is Niacin Max?
NiacinMax is the supplement designed for revolutionary fitness, sports personals, athletes, and enthusiasts of all levels for unleashing their full potential in terms of physical and mental performance and agility. The main component of NiacinMax supplement is Niacin that is a form of Vitamin B3 – also called Nicotinic acid. It helps the cell within your body to create energy from fats, carbs, and proteins.
It also supports oxygen circulation through blood, boosting the levels of blood oxygen. The higher is your level of oxygen in the blood; the higher your achievement will be in your performance. In short, Niacin targets cell functioning to deliver many of the health advantages consequently, increasing sports performance in athletes.
Benefits of NiacinMax supplement
Apart from sports performance-related benefits that you are looking for, Niacin comes with a complex set of entire health and fitness beneficiaries. You can go through the list of services with a brief explanation –
Production Gain and Protection of Red Blood Cells As an athlete, you might go for an intensive workout where your body produces reactive oxygen species and free radicals, which might destruct your blood cells, reducing aerobic performance, and affect entire health conditions. On average, the athlete’s blood cells lifespan is 41.66% shorter compared to an average person, whereas a proper diet can help you out, but sometimes it is not enough.
What will surprise you is that –Niacin plays the role of natural antioxidants, giving your body an additional layer of protection against this red blood cell destruction. It is designed to control the cell-damaging rate with the maintenance of your total blood cells.
Higher Blood Oxygen Levels and Oxygen Flow Blood oxygen level should be high if you are investing yourself in an exhausting workout for your muscles to work better. And this is the reason why athletes use illegal drugs or steroids for boosting VO2 max (maximum oxygen uptake), which results in higher endurance, power, and stamina for one additional rep or any long high-intensity challenge. And because the use of drugs and steroids are against the law, all such benefits can be obtained and an individual can increase blood oxygen circulation naturally, especially athletes whose primary focus is on stamina and endurance are leaning towards supplements like NiacinMax.
Lower “Bad” and Increase “Good” Cholesterol Niacin is helpful in the treatment of high cholesterol. Niacin, despite not being the critical component to treat high cholesterol, studies proved that it could lower your bad cholesterol by 5% to 20%.
Prevention of heart disorders A link between oxygen flow and blood oxygen levels could prevent heart disorders related to cholesterol.
Improving brain functions Niacin supplement delivers high energy to your brain through coenzymes NAD and NADP. It results in sharper focus with power during your HIIT workouts and endurance training.
Other benefits
Increase cell respiration (supply of oxygen to the body)
Reduce the risk of cardiac issues
Reduce fast aging along with body degeneration
It helps to reduce fats from tissues and the bloodstream
Increases the growth of muscles by elevating growth hormone production.
It improves the detoxification process of the body.
Help to raise the secretion of HCL in your stomach during indigestion.
It improves and maintains healthy skin and hair
Speedy recovery from intense workouts
Decreases fatigue and motivates you to reach optimum performance level physically.
Dosage of NiacinMax
To consume this peppermint-flavored NiacinMax supplement spray it thrice in your mouth to get one dose. One dose means 15 mg of fully absorbed Niacin that directly reaches your bloodstream. Intake this dose in the morning immediately after waking up on an empty stomach and scheduling it 3 to 5 hours after your workout session for the best results. If you are playing the role of a heavy-duty athlete, then take one more dose 3 to 4 hours before bed.
Why is NiacinMax better than other Niacin or Vitamin B3 Supplements?
The main difference that makes NiacinMax better than any other Niacin supplement is its unique method of absorption and delivery. It is made to solve issues related to indigestion with its quicker absorption through the direct cell delivery method. NiacinMax supplement is packed in a spray bottle that gets dissolved in your mouth rather than traditional pills, giving effective and faster absorption results.
On the other hand, NiacinMax makes use of liposomal technology which plays a role of protective layer against the breakdown of nutrients until the Niacin researches the cells for utilization. Hence, this liposomal encapsulation feature protects Niacin unless it is assimilated into your body cells. Apart from this, NiacinMax has no side effects like other niacin products, which often give you an upset stomach, a disturbing gastrointestinal tract, avoiding heavy flushing, and offers a 67 days money-back guarantee at the same time. Therefore, it is considered safe to consume.
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What are the Safety levels of the NiacinMax?
NiacinMax consists of the vital vitamin Niacin that is Vitamin B3, needed to boost both mental and physical health. Considering NiacinMax as an advanced and safe formula made up of pure natural and scientifically backed up ingredients, it is clinically tested to ensure all the secured standards that are laid down by leading authorities. It is safe to be consumed by adults, but before using, ensure to consult with a doctor if you have a pre-diagnosed medical condition that was reported.
What is the Price of NiacinMax?
NiacinMax
Retail Price (USD)
Special Discount Price (USD)
Buy 1:
$49.99
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Where to Buy Niacin Max?
Visit Niacin Max Official Website.
Testimonials
Daniel Row (Canada):- “Initially, after workouts, I used to break down and get tired. I felt so tired the entire day like I did not have the energy to continue the routine work. But then, with research and doctor’s consultation, I finally started to consume NiacinMAX as recommended. And seriously, it works. I got a real boost to my energy level, and I am grateful.”
Catherine Levy (United Kingdom):- I was suffering from cholesterol issues. The doctor prescribed medication which I was taking daily, but still, there were minor changes. And I came across the benefits of NiacinMax and took suggestions from the doctor. And it was my fortune that it helped me to maintain my healthy levels of cholesterol along with energy.”
Stuart Reid (Australia):- “I was very much concerned about my hair and skin aging, and so I started consuming NiacinMax. And the results are pleasing enough.”
Conclusion
Therefore, it can be concluded that NiacinMax is a safe form of niacin that one may take without having to encounter any side effects. But, at higher amounts used for treating medical conditions, it can have huge risks. For that particular reason, women who are breastfeeding or pregnant and children must stay away from Niacin supplements unless and until it is suggested to you by your doctor.
But if you are a professional athlete who focuses on endurance, performance, and strength where every millisecond matter, NiacinMax is the best shot for them. NiacinMax is the ultimate vitamin B3, aka, niacin supplement, that has the best absorption rate out of all the competitors on the market and thus is effective in showing results within a span of few minutes.
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Nicotinic acid and niacinamide can both treat pellagra, but niacinamide is preferred since it's associated with fewer side effects, such as flushing of the skin. Niacinamide is a form of vitamin B3, an essential nutrient that supports many cellular processes.
Vitamin B3 is one of 8 B vitamins. It is also known as niacin (nicotinic acid) and has 2 other forms, niacinamide (nicotinamide) and inositol hexanicotinate, which have different effects from niacin.
You'll find both niacin and niacinamide as supplements, and both are forms of vitamin B-3. These can be used interchangeably for some purposes, but some therapies require different forms of the vitamin.
The study showed for the first time that oral NR is superior to nicotinamide, which is better than niacin in terms of the total amount of NAD+ produced at an equivalent dose. NR was also the best of the three in stimulating the activity of sirtuin enzymes.
Children should avoid taking niacinamide doses above the daily upper limits, which are 10 mg for children 1-3 years of age, 15 mg for children 4-8 years of age, 20 mg for children 9-13 years of age, and 30 mg for children 14-18 years of age. Diabetes: Niacinamide might increase blood sugar.
In medical circles, niacinamide is known for being extremely effective when it comes to treating acne, redness, hyperpigmentation, and signs of aging — plus it's compatible with all skin types. Niacin, on the other hand, is more popularly known in the wellness world for supporting cardiovascular health.
The supplement has been linked with liver damage, can cause hypotension and might activate a peptic ulcer. Taking niacin also might worsen allergies, gallbladder disease and symptoms of certain thyroid disorders. If you have diabetes, niacin can interfere with blood glucose control.
They could interact with medicines like diabetes drugs, blood thinners, anticonvulsants, blood pressure medicines, thyroid hormones, and antibiotics as well as supplements like ginkgo biloba and some antioxidants. Alcohol might increase the risk of liver problems.
Niacin, also known as vitamin B3, is an important nutrient. In fact, every part of your body needs it to function properly. As a supplement, niacin may help lower cholesterol, ease arthritis, and boost brain function, among other benefits. However, it can also cause serious side effects if you take large doses.
Niacin in the form of nicotinamide has fewer side effects than nicotinic acid. However, at high doses of 500 mg/day or more, nicotinamide can cause diarrhea, easy bruising, and can increase bleeding from wounds. Even higher doses of 3,000 mg/day or more can cause nausea, vomiting, and liver damage.
If you're taking the extended-release form of niacin, take the medication at bedtime after you eat a low-fat snack such as fruit, pretzels, or carrots. This lowers your risk of side effects like flushing and stomach upset.
Nicotinic acid (niacin) is a well-established treatment for dyslipidaemia – an important cardiovascular disease (CVD) risk factor. However, niacin may also reduce blood pressure (BP), which is another important CVD risk factor.
A severe niacin deficiency leads to pellagra, a condition that causes a dark, sometimes scaly rash to develop on skin areas exposed to sunlight; bright redness of the tongue; and constipation/diarrhea. Other signs of severe niacin deficiency include: Depression. Headache.
Niacinamide might harm the liver, especially when used in high doses. Taking niacinamide along with medication that might also harm the liver can increase the risk of liver damage. Do not take niacinamide if you are taking a medication that can harm the liver.
Conclusion. Our data demonstrate that niacinamide could enhance hair growth by preventing oxidative stress-induced cell senescence and premature catagen entry of hair follicles.
Why it might not be working: If the product is pilling, that means it's not properly absorbed into the skin and, because it's not being absorbed, it's not delivering results. If you experience redness or burning, your skin is likely sensitive to the ingredient.
Introduction. One potentially important side effect known to occur on niacin is a rise in glucose levels in those with diabetes. 5 Findings from a post-hoc analysis of the Coronary Drug Project suggested that this effect also occurred in those without diabetes, leading to an increase in the risk of developing diabetes.
Niacinamide reduces inflammation , which may help ease redness from eczema, acne, and other inflammatory skin conditions. Minimizes pore appearance. Keeping skin smooth and moisturized may have a secondary benefit — a natural reduction in pore size over time.
Niacin (nicotinic acid, vitamin B3) was considered a promising candidate to prevent cardiovascular disease because it is known to lower cholesterol in the blood, which is one of the main risk factors. Therefore, long‐term therapy with niacin was assumed to reduce the risk of heart attack, and stroke.
Because niacin has also been linked to liver damage and strokes, most doctors now recommend it only for people who can't take statins to treat high triglyceride levels.
Vitamin B3 and B12 are two types of vitamin B complexes. The key difference between vitamin B3 and B12 is that vitamin B3 is important in controlling cholesterol and triglyceride levels in our blood, whereas vitamin B12 is important as a cofactor in DNA synthesis for both fatty acid and amino acid metabolism.
Niacin (also known as vitamin B3) is one of the water-soluble B vitamins. Niacin is the generic name for nicotinic acid (pyridine-3-carboxylic acid), nicotinamide (niacinamide or pyridine-3-carboxamide), and related derivatives, such as nicotinamide riboside [1-3].
Niacin serves another purpose: assisting in healthy hair growth. It improves blood circulation, and therefore brings oxygen to the hair follicles, resulting in hair development. 2 It's often recommended to those who have alopecia, with the goal of fuller, thicker hair.
Virtually all niacin users initially experience flushing,19 typically commencing 15 to 30 minutes after ingesting immediate-release niacin, 30 to 120 minutes after ingesting extended-release niacin, or at more variable times after sustained-release niacin ingestion.
The nicotinic acid form of niacin lowers cholesterol, but other forms of niacin do not. These other forms that do not lower cholesterol include nicotinamide and inositol nicotinate (also called no-flush niacin). Ask your doctor how much niacin you should take. You want to take a dose that will work.
Small clinical trials of using niacin have shown it has significant blood pressure lowering effects in people with hypertension. Additionally, sudden lowering of blood pressure is described in the package insert of prescription niacin.
One study found that niacinamide (not niacin) helped people get through withdrawal from benzodiazepines—a common problem. A reasonable amount of niacinamide to take for anxiety, according to some doctors, is up to 500 mg four times per day.
Vitamin B3 is found naturally in a wide variety of both animal and plant-based foods, including beef, liver, poultry, eggs, dairy products, fish, nuts, seeds, legumes, avocados, and whole grains. It is also found in fortified cereals and bread. Vitamin B3 can also be produced in the body from the amino acid tryptophan.
The authors recommended that low-dose niacin is efficient and very well tolerated, which makes it ideal for the treatment of CKD patients with hyperlipidemia and hyperphosphatemia. Niacin (nicotinic acid, vitamin B3) is a water-soluble vitamin that is critical for cellular metabolism [12].
There is evidence to suggest that vitamin B3 can assist with sleeping, which means that another unique property about niacin is its ability to be a wonderful and natural sleeping aid via its interaction with tryptophan.
It increases maximal muscle working capacity, reduces or completely eliminates arthritic joint pain.” As the body is unable to absorb more than 250 mg of niacinamide at a time, it is more effective to take smaller does more often (perhaps every one to three hours) than one large dose per day.
A common side effect of niacin is a flushing reaction. This might cause burning, itching, and redness of the face, arms, and chest, as well as headaches. Starting with small doses and taking 325 mg of aspirin before each dose of niacin may help. This reaction usually goes away as the body gets used to niacin.
The vegetable highest in niacin is spirulina, also known as seaweed. A cup of dried spirulina will meet your entire day's requirements of niacin, with 14 milligrams per cup.
CONCLUSION: Based on the results of this investigation we have demonstrated that acute niacin supplementation of 1000mg significantly decreased resting systolic and diastolic blood pressure, and resting heart rate post-consumption.
Niacin dilates the blood vessels in the skin, especially in the upper body. A dose of 100 mg taken on an empty stomach may cause flushing of the skin. This may also cause intense itching or burning.
This is slightly above average for energy drinks — 5 Hour Energy shots contain 30 mg niacin (150% daily recommended intake), Monster Energy drink contains 24 mg niacin, Red Bull cans contain 25 mg niacin and a can of Rockstar Energy contains a whopping 47 mg niacin.
Side effects may include diarrhea, headache, stomach discomfort, and bloating. High doses (50 mg or more) of niacin can cause side effects. The most common side effect is called "niacin flush," which is a burning, tingling sensation in the face and chest, and red or flushed skin.
A Niacin blood test is typically ordered when a person has symptoms of Niacin deficiency or is taking Niacin supplements to help monitor their levels. Turnaround for this test is typically 2-6 business days.
Improves skin health. Niacin helps protect skin cells from sun damage, whether it's used orally or applied as a lotion ( 17 ). It may help prevent certain types of skin cancer as well.
People use prescription niacin (Niacor, Niaspan) to help control their cholesterol. The recommended daily amount of niacin for adult males is 16 milligrams (mg) a day and for adult women who aren't pregnant, 14 mg a day.
Nicotinic acid supplements contain high amounts, up to 1,000-2,000 mg of niacin taken daily. Studies have shown that they can increase HDL cholesterol and lower LDL cholesterol and triglycerides.
In general, the immediate-release form of niacin should be taken after your evening meal and the extended-release form should be taken at bedtime after a low-fat snack. Taking it in the morning or on an empty stomach might cause you to experience more side effects such as flushing and stomach upset.
In skincare, niacin or niacinamide is used for its ability to promote the formation of healthy skin cells. It also helps increase blood flow and oxygenation, reduce the appearance of wrinkles, treat sun-damaged and dull-looking skin, and tone the skin.
Results: Analyses of the data revealed a variety of significant skin appearance improvement effects for topical niacinamide: reductions in fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness (yellowing). In addition, elasticity (as measured via cutometry) was improved.
Niacin serves another purpose: assisting in healthy hair growth. It improves blood circulation, and therefore brings oxygen to the hair follicles, resulting in hair development. 2 It's often recommended to those who have alopecia, with the goal of fuller, thicker hair.
They could interact with medicines like diabetes drugs, blood thinners, anticonvulsants, blood pressure medicines, thyroid hormones, and antibiotics as well as supplements like ginkgo biloba and some antioxidants. Alcohol might increase the risk of liver problems.
Nicotinic acid (niacin) is a well-established treatment for dyslipidaemia – an important cardiovascular disease (CVD) risk factor. However, niacin may also reduce blood pressure (BP), which is another important CVD risk factor.
One medium avocado contains 3.5 mg of niacin, or 21% and 25% of the RDA for men and women, respectively (29). They're also rich in fiber, healthy fats and many vitamins and minerals. In fact, one avocado contains more than twice the potassium of a banana (29, 30).
Both studies revealed that niacin supplementation induces muscle fiber transition from type II to type I and increases the number of type I fibers in skeletal muscle [14,15].
Adults and children older than 16 years of age—At first, 500 milligrams (mg) per day, taken at bedtime. After 4 weeks, your doctor will increase your dose to 1000 mg per day, taken at bedtime. However, the dose is usually not more than 2000 mg per day.
There is evidence to suggest that vitamin B3 can assist with sleeping, which means that another unique property about niacin is its ability to be a wonderful and natural sleeping aid via its interaction with tryptophan.
Introduction: My name is Tyson Zemlak, I am a excited, light, sparkling, super, open, fair, magnificent person who loves writing and wants to share my knowledge and understanding with you.
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